Human HPS3 activation kit by CRISPRa

CAT#: GA113532

HPS3 CRISPRa kit - CRISPR gene activation of human HPS3 biogenesis of lysosomal organelles complex 2 subunit 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HPS3
• Locus ID: 84343
• Kit Components:

  GA113532G1, HPS3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113532G2, HPS3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113532G3, HPS3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001308258, NM_032383
• Synonyms: BLOC2S1; SUTAL
• Summary: This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. [provided by RefSeq, Apr 2015]