Human Prokineticin 1 (PROK1) activation kit by CRISPRa

CAT#: GA113540

PROK1 CRISPRa kit - CRISPR gene activation of human prokineticin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PROK1
• Locus ID: 84432
• Kit Components:

  GA113540G1, PROK1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113540G2, PROK1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113540G3, PROK1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032414
• Synonyms: EGVEGF; PK1; PRK1
• Summary: The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011]