Human SYVN1 activation kit by CRISPRa

CAT#: GA113552

SYVN1 CRISPRa kit - CRISPR gene activation of human synoviolin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SYVN1
• Locus ID: 84447
• Kit Components:

  GA113552G1, SYVN1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113552G2, SYVN1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113552G3, SYVN1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032431, NM_172230
• Synonyms: DER3; HRD1
• Summary: This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq, May 2011]