Human JPH4 activation kit by CRISPRa

CAT#: GA113569

JPH4 CRISPRa kit - CRISPR gene activation of human junctophilin 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: JPH4
• Locus ID: 84502
• Kit Components:

  GA113569G1, JPH4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113569G2, JPH4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113569G3, JPH4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001146028, NM_032452
• Synonyms: JP4; JPHL1
• Summary: This gene encodes a member of the junctophilin family of transmembrane proteins that are involved in the formation of the junctional membrane complexes between the plasma membrane and the endoplasmic/sarcoplasmic reticulum in excitable cells. The encoded protein contains a conserved N-terminal repeat region called the membrane occupation and recognition nexus sequence that is found in other members of the junctophilin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]