Human HOPX activation kit by CRISPRa

CAT#: GA113582

HOPX CRISPRa kit - CRISPR gene activation of human HOP homeobox

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HOPX
• Locus ID: 84525
• Kit Components:

  GA113582G1, HOPX gRNA vector 1 in pCas-Guide-CRISPRa

  GA113582G2, HOPX gRNA vector 2 in pCas-Guide-CRISPRa

  GA113582G3, HOPX gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145459, NM_001145460, NM_032495, NM_139211, NM_139212
• Synonyms: CAMEO; HOD; HOP; LAGY; NECC1; OB1; SMAP31; TOTO
• Summary: The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Feb 2009]