Human Ovary specific acidic protein (MGARP) activation kit by CRISPRa

CAT#: GA113671

MGARP CRISPRa kit - CRISPR gene activation of human mitochondria localized glutamic acid rich protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MGARP
• Locus ID: 84709
• Kit Components:

  GA113671G1, MGARP gRNA vector 1 in pCas-Guide-CRISPRa

  GA113671G2, MGARP gRNA vector 2 in pCas-Guide-CRISPRa

  GA113671G3, MGARP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032623
• Synonyms: C4orf49; CESP-1; HUMMR; OSAP
• Summary: Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology. [UniProtKB/Swiss-Prot Function]