Human ADO activation kit by CRISPRa

CAT#: GA113742

ADO CRISPRa kit - CRISPR gene activation of human 2-aminoethanethiol dioxygenase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADO
• Locus ID: 84890
• Kit Components:

  GA113742G1, ADO gRNA vector 1 in pCas-Guide-CRISPRa

  GA113742G2, ADO gRNA vector 2 in pCas-Guide-CRISPRa

  GA113742G3, ADO gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032804
• Synonyms: C10orf22
• Summary: Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine (Dominy et al., 2007 [PubMed 17581819]). [supplied by OMIM, Mar 2008]