Human PWWP3A activation kit by CRISPRa

CAT#: GA113784

PWWP3A CRISPRa kit - CRISPR gene activation of human PWWP domain containing 3A, DNA repair factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PWWP3A
• Locus ID: 84939
• Kit Components:

  GA113784G1, PWWP3A gRNA vector 1 in pCas-Guide-CRISPRa

  GA113784G2, PWWP3A gRNA vector 2 in pCas-Guide-CRISPRa

  GA113784G3, PWWP3A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032853, NR_024247, NM_001369791, NM_001369796, NM_001369797, NM_001369789, NM_001369790, NM_001369792, NM_001369793, NM_001369794, NM_001369795, NR_163148, NR_163149
• Synonyms: EXPAND1; HSPC211; MUM-1
• Summary: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. [UniProtKB/Swiss-Prot Function]