Human C3Orf34 (CEP19) activation kit by CRISPRa

CAT#: GA113815

CEP19 CRISPRa kit - CRISPR gene activation of human centrosomal protein 19

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CEP19
• Locus ID: 84984
• Kit Components:

  GA113815G1, CEP19 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113815G2, CEP19 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113815G3, CEP19 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032898
• Synonyms: C3orf34; MOSPGF
• Summary: The protein encoded by this gene localizes to centrosomes and primary cilia and co-localizes with a marker for the mother centriole. This gene resides in a region of human chromosome 3 that is linked to morbid obesity. A homozygous knockout of the orthologous gene in mouse resulted in mice with morbid obesity, hyperphagy, glucose intolerance, and insulin resistance. Mutations in this gene cause morbid obesity and spermatogenic failure (MOSPGF). This gene has a pseudogene on human chromosome 2. [provided by RefSeq, Apr 2014]