Human ZIC5 activation kit by CRISPRa

CAT#: GA113877

ZIC5 CRISPRa kit - CRISPR gene activation of human Zic family member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZIC5
• Locus ID: 85416
• Kit Components:

  GA113877G1, ZIC5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113877G2, ZIC5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113877G3, ZIC5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_033132, NR_146224, NR_146225
• Synonyms: OTTHUMP00000040732; Zic family member 5 (odd-paired homolog, Drosophila); zinc family member 5 protein; zinc finger protein of the cerebellum 5
• Summary: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. The encoded protein may act as a transcriptional repressor. Studies in mouse and Xenopus support a role for this gene in neural crest development. Elevated expression of this gene has been observed in various human cancers and may contribute to cancer progression. This gene is closely linked to a related family member on chromosome 13. [provided by RefSeq, Mar 2017]