Human ZIC5 activation kit by CRISPRa

CAT#: GA113877

ZIC5 CRISPRa kit - CRISPR gene activation of human Zic family member 5


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol ZIC5
Locus ID 85416
Kit Components

GA113877G1, ZIC5 gRNA vector 1 in pCas-Guide-CRISPRa

GA113877G2, ZIC5 gRNA vector 2 in pCas-Guide-CRISPRa

GA113877G3, ZIC5 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_033132, NR_146224, NR_146225
Synonyms OTTHUMP00000040732; Zic family member 5 (odd-paired homolog, Drosophila); zinc family member 5 protein; zinc finger protein of the cerebellum 5
Summary This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. The encoded protein may act as a transcriptional repressor. Studies in mouse and Xenopus support a role for this gene in neural crest development. Elevated expression of this gene has been observed in various human cancers and may contribute to cancer progression. This gene is closely linked to a related family member on chromosome 13. [provided by RefSeq, Mar 2017]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.