Human GFM1 activation kit by CRISPRa

CAT#: GA113906

GFM1 CRISPRa kit - CRISPR gene activation of human G elongation factor mitochondrial 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GFM1
• Locus ID: 85476
• Kit Components:

  GA113906G1, GFM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113906G2, GFM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113906G3, GFM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001308164, NM_001308166, NM_024996
• Synonyms: COXPD1; EFG; EFG1; EFGM; EGF1; GFM; hEFG1
• Summary: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. [provided by RefSeq, Jul 2008]