Human GALP activation kit by CRISPRa

CAT#: GA113914

GALP CRISPRa kit - CRISPR gene activation of human galanin like peptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GALP
• Locus ID: 85569
• Kit Components:

  GA113914G1, GALP gRNA vector 1 in pCas-Guide-CRISPRa

  GA113914G2, GALP gRNA vector 2 in pCas-Guide-CRISPRa

  GA113914G3, GALP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145546, NM_033106
• Synonyms: alarin (splice variant); galanin-like peptide
• Summary: This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, has vasoactive properties, displays antimicrobial activity against E. coli, and may serve as a marker for neuroblastic tumors. [provided by RefSeq, Nov 2014]