Human WNT3A activation kit by CRISPRa

CAT#: GA113926

WNT3A CRISPRa kit - CRISPR gene activation of human Wnt family member 3A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WNT3A
• Locus ID: 89780
• Kit Components:

  GA113926G1, WNT3A gRNA vector 1 in pCas-Guide-CRISPRa

  GA113926G2, WNT3A gRNA vector 2 in pCas-Guide-CRISPRa

  GA113926G3, WNT3A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_033131
• Synonyms: MGC119418; MGC119419; MGC119420
• Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. [provided by RefSeq, Jul 2008]