Human SLC25A21 activation kit by CRISPRa

CAT#: GA113949

SLC25A21 CRISPRa kit - CRISPR gene activation of human solute carrier family 25 member 21

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC25A21
• Locus ID: 89874
• Kit Components:

  GA113949G1, SLC25A21 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113949G2, SLC25A21 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113949G3, SLC25A21 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001171170, NM_030631
• Synonyms: ODC; ODC1
• Summary: SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA. [supplied by OMIM, Apr 2004]