Human HS6ST2 activation kit by CRISPRa

CAT#: GA113983

HS6ST2 CRISPRa kit - CRISPR gene activation of human heparan sulfate 6-O-sulfotransferase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HS6ST2
• Locus ID: 90161
• Kit Components:

  GA113983G1, HS6ST2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113983G2, HS6ST2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113983G3, HS6ST2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001077188, NM_147174, NM_147175
• Synonyms: MGC130022; MGC130023
• Summary: Heparan sulfate proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various ligands to influence cell growth, differentiation, adhesion, and migration. This gene encodes a member of the heparan sulfate (HS) sulfotransferase gene family, which catalyze the transfer of sulfate to HS. Different family members and isoforms are thought to synthesize heparan sulfates with tissue-specific structures and functions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]