Human LYRM7 activation kit by CRISPRa

CAT#: GA114041

LYRM7 CRISPRa kit - CRISPR gene activation of human LYR motif containing 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LYRM7
• Locus ID: 90624
• Kit Components:

  GA114041G1, LYRM7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114041G2, LYRM7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114041G3, LYRM7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001293735, NM_181705, NR_121658
• Synonyms: C5orf31; MC3DN8; MZM1L
• Summary: Inner mitochondrial membrane complex III (CIII) is the main enzyme complex in the mitochondrial respiratory chain, and Rieske Fe-S protein (UQCRFS1) is the last catalytic subunit added to the complex. The protein encoded by this gene is a nuclear-encoded mitochondrial matrix protein that stabilizes UQCRFS1 and chaperones it to the CIII complex. Defects in this gene are a cause of mitochondrial complex III deficiency, nuclear type 8. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]