Human STARD13 activation kit by CRISPRa

CAT#: GA114043

STARD13 CRISPRa kit - CRISPR gene activation of human StAR related lipid transfer domain containing 13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: STARD13
• Locus ID: 90627
• Kit Components:

  GA114043G1, STARD13 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114043G2, STARD13 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114043G3, STARD13 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001243466, NM_001243474, NM_001243476, NM_052851, NM_178006, NM_178007, NM_178008
• Synonyms: ARHGAP37; DLC2; GT650; LINC00464
• Summary: This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]