Human Lass5 (CERS5) activation kit by CRISPRa

CAT#: GA114080

CERS5 CRISPRa kit - CRISPR gene activation of human ceramide synthase 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CERS5
• Locus ID: 91012
• Kit Components:

  GA114080G1, CERS5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114080G2, CERS5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114080G3, CERS5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001281731, NM_001331069, NM_001331070, NM_001331071, NM_001331072, NM_001331073, NM_147190, NR_104035, NR_138532, NR_138533, NR_138534, NR_138535, NR_138536
• Synonyms: LASS5; Trh4
• Summary: This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]