Human Nexilin (NEXN) activation kit by CRISPRa

CAT#: GA114133

NEXN CRISPRa kit - CRISPR gene activation of human nexilin F-actin binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NEXN
• Locus ID: 91624
• Kit Components:

  GA114133G1, NEXN gRNA vector 1 in pCas-Guide-CRISPRa

  GA114133G2, NEXN gRNA vector 2 in pCas-Guide-CRISPRa

  GA114133G3, NEXN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001172309, NM_144573
• Synonyms: CMH20; NELIN
• Summary: This gene encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]