Human CRB3 activation kit by CRISPRa

CAT#: GA114211

CRB3 CRISPRa kit - CRISPR gene activation of human crumbs cell polarity complex component 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CRB3
• Locus ID: 92359
• Kit Components:

  GA114211G1, CRB3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114211G2, CRB3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114211G3, CRB3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_139161, NM_174881, NM_174882
• Synonyms: crumbs 3; crumbs homolog 3 (Drosophila); MGC17303
• Summary: This gene encodes a member of the Crumbs family of proteins. This gene is widely expressed in epithelial tissues where the encoded protein isoforms play various roles such as the control of cytokinesis and ciliogenesis or the formation of tight junctions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]