Human HNRPLL (HNRNPLL) activation kit by CRISPRa

CAT#: GA114248

HNRNPLL CRISPRa kit - CRISPR gene activation of human heterogeneous nuclear ribonucleoprotein L like


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol HNRNPLL
Locus ID 92906
Kit Components

GA114248G1, HNRNPLL gRNA vector 1 in pCas-Guide-CRISPRa

GA114248G2, HNRNPLL gRNA vector 2 in pCas-Guide-CRISPRa

GA114248G3, HNRNPLL gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001142650, NM_138394
Synonyms HNRPLL; SRRF
Summary HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]). [supplied by OMIM, Aug 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.