Human Myocardin (MYOCD) activation kit by CRISPRa

CAT#: GA114298

MYOCD CRISPRa kit - CRISPR gene activation of human myocardin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MYOCD
• Locus ID: 93649
• Kit Components:

  GA114298G1, MYOCD gRNA vector 1 in pCas-Guide-CRISPRa

  GA114298G2, MYOCD gRNA vector 2 in pCas-Guide-CRISPRa

  GA114298G3, MYOCD gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001146312, NM_001146313, NM_153604
• Synonyms: MYCD
• Summary: This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]