Human CPA5 activation kit by CRISPRa

CAT#: GA114308

CPA5 CRISPRa kit - CRISPR gene activation of human carboxypeptidase A5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CPA5
• Locus ID: 93979
• Kit Components:

  GA114308G1, CPA5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114308G2, CPA5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114308G3, CPA5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127441, NM_001127442, NM_001318223, NM_080385
• Synonyms: FLJ35969
• Summary: Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002 [PubMed 11836249]). [supplied by OMIM, Mar 2008]