Human Granuphilin (SYTL4) activation kit by CRISPRa

CAT#: GA114333

SYTL4 CRISPRa kit - CRISPR gene activation of human synaptotagmin like 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SYTL4
• Locus ID: 94121
• Kit Components:

  GA114333G1, SYTL4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114333G2, SYTL4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114333G3, SYTL4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001129896, NM_001174068, NM_080737, NM_001370161, NM_001370162, NM_001370164, NM_001370166, NM_001370168, NM_001370160, NM_001370163, NM_001370165, NM_001370167, NM_001370169
• Synonyms: SLP4
• Summary: This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Mar 2010]