Human PPP1R14A activation kit by CRISPRa

CAT#: GA114344

PPP1R14A CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory inhibitor subunit 14A


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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol PPP1R14A
Locus ID 94274
Kit Components

GA114344G1, PPP1R14A gRNA vector 1 in pCas-Guide-CRISPRa

GA114344G2, PPP1R14A gRNA vector 2 in pCas-Guide-CRISPRa

GA114344G3, PPP1R14A gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001243947, NM_033256
Synonyms CPI-17; CPI17; PPP1INL
Summary The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.