Human MRAP2 activation kit by CRISPRa

CAT#: GA114359

MRAP2 CRISPRa kit - CRISPR gene activation of human melanocortin 2 receptor accessory protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MRAP2
• Locus ID: 112609
• Kit Components:

  GA114359G1, MRAP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114359G2, MRAP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114359G3, MRAP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_138409, NM_001346541, NM_001346542, NM_001346543, NM_001346544
• Synonyms: bA51G5.2; BMIQ18; C6orf117
• Summary: This gene encodes a protein that modulates melanocortin receptor signaling. The encoded protein has been shown to interact with all known melanocortin receptors and may regulate both receptor trafficking and activation in response to ligands. Mice lacking a functional copy of this gene exhibit severe obesity and a mutation in this gene may be associated with severe obesity in human patients. [provided by RefSeq, Oct 2016]