Human PGRPL (PGLYRP2) activation kit by CRISPRa

CAT#: GA114444

PGLYRP2 CRISPRa kit - CRISPR gene activation of human peptidoglycan recognition protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PGLYRP2
• Locus ID: 114770
• Kit Components:

  GA114444G1, PGLYRP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114444G2, PGLYRP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114444G3, PGLYRP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_052890, NM_001363546
• Synonyms: HMFT0141; PGLYRPL; PGRP-L; PGRPL; tagL; tagL-alpha; tagl-beta; TAGL-like
• Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011]