Human SLITRK1 activation kit by CRISPRa

CAT#: GA114461

SLITRK1 CRISPRa kit - CRISPR gene activation of human SLIT and NTRK like family member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLITRK1
• Locus ID: 114798
• Kit Components:

  GA114461G1, SLITRK1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114461G2, SLITRK1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114461G3, SLITRK1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001281503, NM_052910
• Synonyms: LRRC12; TTM
• Summary: This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. However, the protein encoded by this gene lacks the region of homology to neurotrophin receptors. This protein is thought to be involved in neurite outgrowth. Mutations in this gene may be associated with Tourette syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]