Human ORP1 (OSBPL1A) activation kit by CRISPRa

CAT#: GA114478

OSBPL1A CRISPRa kit - CRISPR gene activation of human oxysterol binding protein like 1A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OSBPL1A
• Locus ID: 114876
• Kit Components:

  GA114478G1, OSBPL1A gRNA vector 1 in pCas-Guide-CRISPRa

  GA114478G2, OSBPL1A gRNA vector 2 in pCas-Guide-CRISPRa

  GA114478G3, OSBPL1A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242508, NM_018030, NM_080597, NM_133268
• Synonyms: ORP-1; ORP1; OSBPL1B
• Summary: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008]