Human GBP5 activation kit by CRISPRa

CAT#: GA114525

GBP5 CRISPRa kit - CRISPR gene activation of human guanylate binding protein 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GBP5
• Locus ID: 115362
• Kit Components:

  GA114525G1, GBP5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114525G2, GBP5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114525G3, GBP5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001134486, NM_052942
• Synonyms: GBP-5
• Summary: This gene belongs to the TRAFAC class dynamin-like GTPase superfamily. The encoded protein acts as an activator of NLRP3 inflammasome assembly and has a role in innate immunity and inflammation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017]