Human SLC22A12 activation kit by CRISPRa

CAT#: GA114562

SLC22A12 CRISPRa kit - CRISPR gene activation of human solute carrier family 22 member 12

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC22A12
• Locus ID: 116085
• Kit Components:

  GA114562G1, SLC22A12 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114562G2, SLC22A12 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114562G3, SLC22A12 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001276326, NM_001276327, NM_144585, NM_153378
• Synonyms: OAT4L; RST; URAT1
• Summary: The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]