Human CYP2R1 activation kit by CRISPRa

CAT#: GA114713

CYP2R1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 2 subfamily R member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP2R1
• Locus ID: 120227
• Kit Components:

  GA114713G1, CYP2R1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114713G2, CYP2R1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114713G3, CYP2R1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024514
• Synonyms: MGC4663
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008]