Human Tryptophan 5 hydroxylase 2 (TPH2) activation kit by CRISPRa

CAT#: GA114744

TPH2 CRISPRa kit - CRISPR gene activation of human tryptophan hydroxylase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TPH2
• Locus ID: 121278
• Kit Components:

  GA114744G1, TPH2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114744G2, TPH2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114744G3, TPH2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_173353
• Synonyms: ADHD7; NTPH
• Summary: This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016]