Human FOXN4 activation kit by CRISPRa

CAT#: GA114760

FOXN4 CRISPRa kit - CRISPR gene activation of human forkhead box N4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FOXN4
• Locus ID: 121643
• Kit Components:

  GA114760G1, FOXN4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114760G2, FOXN4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114760G3, FOXN4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_213596
• Synonyms: FLJ35967
• Summary: Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al., 2004 [PubMed 15363391]). [supplied by OMIM, Mar 2008]