Human SOCS4 activation kit by CRISPRa

CAT#: GA114789

SOCS4 CRISPRa kit - CRISPR gene activation of human suppressor of cytokine signaling 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SOCS4
• Locus ID: 122809
• Kit Components:

  GA114789G1, SOCS4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114789G2, SOCS4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114789G3, SOCS4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_080867, NM_199421
• Synonyms: SOCS7
• Summary: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]