Human IQCK activation kit by CRISPRa

CAT#: GA114830

IQCK CRISPRa kit - CRISPR gene activation of human IQ motif containing K

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IQCK
• Locus ID: 124152
• Kit Components:

  GA114830G1, IQCK gRNA vector 1 in pCas-Guide-CRISPRa

  GA114830G2, IQCK gRNA vector 2 in pCas-Guide-CRISPRa

  GA114830G3, IQCK gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001305121, NM_001305122, NM_153208, NR_130967, NR_130968
• Summary: This gene belongs to the IQ motif-containing family of proteins. The IQ motif serves as a binding site for different EF-hand proteins such as calmodulin. This gene was identified as a potential candidate gene for obsessive-compulsive disorder in a genome-wide association study. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]