Human KIST (UHMK1) activation kit by CRISPRa

CAT#: GA115019

UHMK1 CRISPRa kit - CRISPR gene activation of human U2AF homology motif kinase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UHMK1
• Locus ID: 127933
• Kit Components:

  GA115019G1, UHMK1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115019G2, UHMK1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115019G3, UHMK1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001184763, NM_144624, NM_175866
• Synonyms: KIS; KIST; P-CIP2
• Summary: The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]