Human RBM45 activation kit by CRISPRa

CAT#: GA115094

RBM45 CRISPRa kit - CRISPR gene activation of human RNA binding motif protein 45

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RBM45
• Locus ID: 129831
• Kit Components:

  GA115094G1, RBM45 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115094G2, RBM45 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115094G3, RBM45 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_152945, NM_001365578, NM_001365579
• Synonyms: DRB1; RB-1
• Summary: This gene encodes a member of the RNA recognition motif (RRM)-type RNA-binding family of proteins. This protein exhibits preferential binding to poly(C) RNA. Initial cloning of this gene found that the rat ortholog was dynamically expressed in the developing rat brain. This protein has been localized to inclusion bodies in the brain and spinal cord of amyotrophic lateral sclerosis and Alzheimer's patients. A pseudogene has been identified on chromosome 8. [provided by RefSeq, Feb 2015]