Human Activin A Receptor Type IC (ACVR1C) activation kit by CRISPRa

CAT#: GA115111

ACVR1C CRISPRa kit - CRISPR gene activation of human activin A receptor type 1C

SDS

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol ACVR1C
Locus ID 130399
Kit Components

GA115111G1, ACVR1C gRNA vector 1 in pCas-Guide-CRISPRa

GA115111G2, ACVR1C gRNA vector 2 in pCas-Guide-CRISPRa

GA115111G3, ACVR1C gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058
Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001111031, NM_001111032, NM_001111033, NM_145259
Synonyms ACVRLK7; ALK7
Summary ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]). [supplied by OMIM, Mar 2008]

Other Versions

SKU Description Size Price
KN405434 ACVR1C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.