Human DNAJC19 activation kit by CRISPRa

CAT#: GA115137

DNAJC19 CRISPRa kit - CRISPR gene activation of human DnaJ heat shock protein family (Hsp40) member C19

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DNAJC19
• Locus ID: 131118
• Kit Components:

  GA115137G1, DNAJC19 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115137G2, DNAJC19 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115137G3, DNAJC19 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190233, NM_145261, NM_201259, NM_201260, NM_201261, NR_033721, NR_033722, NR_033723, NR_033724, NR_033725, NR_046073
• Synonyms: PAM18; TIM14; TIMM14
• Summary: The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 2, 6, 10, 14 and 19. [provided by RefSeq, Jan 2012]