Human DNAJC21 activation kit by CRISPRa

CAT#: GA115218

DNAJC21 CRISPRa kit - CRISPR gene activation of human DnaJ heat shock protein family (Hsp40) member C21

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DNAJC21
• Locus ID: 134218
• Kit Components:

  GA115218G1, DNAJC21 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115218G2, DNAJC21 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115218G3, DNAJC21 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012339, NM_194283, NM_001348420
• Synonyms: BMFS3; DNAJA5; GS3; JJJ1
• Summary: This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the precursor 45S ribosomal RNA and may be involved in early nuclear ribosomal RNA biogenesis and maturation of the 60S ribosomal subunit. Mutations in this gene result in Bone marrow failure syndrome 3. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2017]