Human LSM11 activation kit by CRISPRa

CAT#: GA115223

LSM11 CRISPRa kit - CRISPR gene activation of human LSM11, U7 small nuclear RNA associated

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LSM11
• Locus ID: 134353
• Kit Components:

  GA115223G1, LSM11 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115223G2, LSM11 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115223G3, LSM11 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_173491
• Synonyms: FLJ38273
• Summary: Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing (By similarity). Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to the Sm-binding site of U7 snRNA. [UniProtKB/Swiss-Prot Function]