Human APOBEC3D activation kit by CRISPRa

CAT#: GA115372

APOBEC3D CRISPRa kit - CRISPR gene activation of human apolipoprotein B mRNA editing enzyme catalytic subunit 3D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: APOBEC3D
• Locus ID: 140564
• Kit Components:

  GA115372G1, APOBEC3D gRNA vector 1 in pCas-Guide-CRISPRa

  GA115372G2, APOBEC3D gRNA vector 2 in pCas-Guide-CRISPRa

  GA115372G3, APOBEC3D gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_152426, NM_001363781
• Synonyms: A3D; APOBEC3DE; APOBEC3E; ARP6
• Summary: This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. [provided by RefSeq, Jul 2008]