Human KRT72 activation kit by CRISPRa

CAT#: GA115411

KRT72 CRISPRa kit - CRISPR gene activation of human keratin 72

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KRT72
• Locus ID: 140807
• Kit Components:

  GA115411G1, KRT72 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115411G2, KRT72 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115411G3, KRT72 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001146225, NM_001146226, NM_080747
• Synonyms: K6irs; K6IRS2; KRT6; KRT6IRS2
• Summary: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]