Human SLC34A3 activation kit by CRISPRa

CAT#: GA115438

SLC34A3 CRISPRa kit - CRISPR gene activation of human solute carrier family 34 member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC34A3
• Locus ID: 142680
• Kit Components:

  GA115438G1, SLC34A3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115438G2, SLC34A3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115438G3, SLC34A3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001177316, NM_001177317, NM_080877
• Synonyms: HHRH; NPTIIc
• Summary: This gene encodes a member of SLC34A transporter family of proteins, and is expressed primarily in the kidney. It is involved in transporting phosphate into cells via sodium cotransport in the renal brush border membrane, and contributes to the maintenance of inorganic phosphate concentration in the kidney. Mutations in this gene are associated with hereditary hypophosphatemic rickets with hypercalciuria. Alternatively spliced transcript variants varying in the 5' UTR have been found for this gene. [provided by RefSeq, Apr 2010]