Human Keratin 80 (KRT80) activation kit by CRISPRa
CAT#: GA115500
KRT80 CRISPRa kit - CRISPR gene activation of human keratin 80
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | KRT80 |
Locus ID | 144501 |
Kit Components | GA115500G1, KRT80 gRNA vector 1 in pCas-Guide-CRISPRa GA115500G2, KRT80 gRNA vector 2 in pCas-Guide-CRISPRa GA115500G3, KRT80 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001081492, NM_182507 |
Synonyms | KB20 |
Summary | Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene. [provided by RefSeq, Oct 2010] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN409155 | KRT80 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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