Human NRG4 activation kit by CRISPRa

CAT#: GA115540

NRG4 CRISPRa kit - CRISPR gene activation of human neuregulin 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NRG4
• Locus ID: 145957
• Kit Components:

  GA115540G1, NRG4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115540G2, NRG4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115540G3, NRG4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_138573
• Synonyms: HRG4
• Summary: The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]). [supplied by OMIM, Mar 2008]