Human Desmoglein 4 (DSG4) activation kit by CRISPRa

CAT#: GA115608

DSG4 CRISPRa kit - CRISPR gene activation of human desmoglein 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DSG4
• Locus ID: 147409
• Kit Components:

  GA115608G1, DSG4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115608G2, DSG4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115608G3, DSG4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001134453, NM_177986
• Synonyms: CDGF13; CDHF13; HYPT6; LAH
• Summary: This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth. [provided by RefSeq, May 2016]