Human KLC3 activation kit by CRISPRa

CAT#: GA115624

KLC3 CRISPRa kit - CRISPR gene activation of human kinesin light chain 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KLC3
• Locus ID: 147700
• Kit Components:

  GA115624G1, KLC3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115624G2, KLC3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115624G3, KLC3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145275, NM_177417
• Synonyms: kinesin light chain 2-like; kinesin light chain 3; KLC2; KLC2, KLCt, KLC2L, KNS2B; KLC2-like; KLC2L; KLCt; KNS2B
• Summary: This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria. [provided by RefSeq, Jul 2008]