Human Synaptotagmin VI (SYT6) activation kit by CRISPRa

CAT#: GA115667

SYT6 CRISPRa kit - CRISPR gene activation of human synaptotagmin 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SYT6
• Locus ID: 148281
• Kit Components:

  GA115667G1, SYT6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115667G2, SYT6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115667G3, SYT6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001253772, NM_001270805, NM_205848, NR_045589, N50928, NM_001366224, NM_001366223, NM_001366225, NM_001366226
• Summary: The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011]